CAS 367-21-5|3-Chloro-4-fluoroaniline|3-chloro-4-fluoroaniline|3-chloro-4-fluoroaniline|3-Chloro-4-fluoroaniline 98%|3-氯-4-氟苯胺|3-Chloro-4-fluoroaniline

InChI=1S/C6H5ClFN/c7-5-3-4(9)1-2-6(5)8/h1-3H,9H2

YSEMCVGMNUUNRK-UHFFFAOYSA-N

H Acceptors

H Donor

LogD (pH = 5.5)

1.8896115

LogD (pH = 7.4)

1.8910481

Log P

1.8910664

Molar Refractivity

35.7796

Polarizability

13.092138

Polar Surface Area

26.02

Rotatable Bonds

Lipinski's Rule of Five

true

3-Chloro-4-fluoroaniline3-Chloro-4-fluoroaniline 98%3-氯-4-氟苯胺3-Chloro-4-fluoroaniline

3-chloro-4-fluoroaniline

IUPAC Traditional name

3-chloro-4-fluoroaniline

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TOXIC

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PC1820

Intermediate for the synthesis of quinoline antibiotic norfloxacin. For an efficient synthesis see: J. Chem. Soc., Chem. Comm., 1339 (1995)

228583

Packaging
25, 100 g in glass bottle

• Reaction with triethyl orthoformate, catalyzed by sulfuric acid, to give the N-ethyl-N-formyl derivative (method as Org. Synth. Coll., 4, 420 (1963)), is the first step in a short and efficient strategy for the synthesis of the quinoline antibiotic norfloxacin: J. Chem. Soc., Chem. Commun., 1319 (1995).

Names and Identifiers

Synonyms

3-Chloro-4-fluoroaniline3-Chloro-4-fluoroaniline 98%3-氯-4-氟苯胺3-Chloro-4-fluoroaniline

IUPAC name

3-chloro-4-fluoroaniline

IUPAC Traditional name

3-chloro-4-fluoroaniline

Registration numbers

PubChem SID

248547872485369624869574160970755

Beilstein Number

MDL Number

EC Number

CAS Number

PubChem CID

Molecule Details

PC1820

Intermediate for the synthesis of quinoline antibiotic norfloxacin. For an efficient synthesis see: J. Chem. Soc., Chem. Comm., 1339 (1995)

Sigma Aldrich

228583

Packaging
25, 100 g in glass bottle

References

PubChem Literature

From Data Sources

Bioactivity

PubChem BioAssay

Toxic/Irritant/Light Sensitive/Keep Cold

TSCA Listed

true

是

UN Number

2811

UN2811

Packing Group

III

GHS Pictograms

Acute toxicity (oral, dermal, inhalation), categories 1,2,3

Respiratory sensitization, category 1

Germ cell mutagenicity, categories 1A,1B,2

Carcinogenicity, categories 1A,1B,2

Reproductive toxicity, categories 1A,1B,2

Specific Target Organ Toxicity – Single exposure, categories 1,2

Specific Target Organ Toxicity – Repeated exposure, categories 1,2

Aspiration Hazard, category 1

GHS Hazard statements

H301-H311-H331-H373

H311-H302-H332-H315-H319-H373

GHS Precautionary statements

P261-P280-P301+P310-P311

P260-P305+P351+P338-P361-P302+P352-P405-P501A

Hazard Class

6.1

Safety Statements

36/37/39-45

26-28-36/37

Personal Protective Equipment

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

German water hazard class

European Hazard Symbols

Toxic (T)

Harmful (X)

GHS Signal Word

Danger

RID/ADR

UN 2811 6.1/PG 2

Risk Statements

23/24/25-33

20/21/22-33-36/38

Molecule

ID:7448