CAS 123-75-1|PYRROLIDINE|pyrrolidine|pyrrolidine|Tetrahydropyrrole|吡咯烷|甲氢氮杂茂|Tetramethyleneimine|Pyrrolidine|四氢吡咯|吡咯烷|Tetramethylenimine|Prolamine|azolidine|NSC 62781|azacyclopentane|...

PYRROLIDINE吡咯烷Pyrrolidine四氢吡咯Tetramethyleneimine甲氢氮杂茂Tetrahydropyrrole吡咯烷ButyleniminePerhydropyrroleNSC 62781azacyclopentaneazolidineTetramethylenimineProlaminePyrrolidine 99%1-Azacyclopentanetetrahydropyrroleprolamineazolidinebutyleniminetetramethylenimine1-azacyclopentaneperhydropyrroleazacyclopentanepyrrolidine

IUPAC name

pyrrolidine

IUPAC Traditional name

pyrrolidine

Names and Identifiers

Registration numbers

PubChem CID

CHEMBL

Beilstein Number

MDL Number

FEMA ID

CAS Number

CHEBI ID

Wikipedia Title

Chemspider ID

Unique Ingredient Identifier

Flavis Number

EC Number

Merck Index

PubChem SID

249017602488810224864581248988441620393058147176

Council of Europe Number

10491

Patent number

US2006019945US2006194783US2005159405EP0812845US2005131016US2005153984WO2005035520WO2005121159EP0999204EP1541582EP0842934US2005288311US2005171098EP1785415

MetaboLights Database

MTBLS2406MTBLS1918MTBLS1739MTBLS3487MTBLS2145MTBLS2878MTBLS560MTBLS1040MTBLS2559MTBLS1115MTBLS1182MTBLS2427MTBLS1411MTBLS4126MTBLS3943

PDBeChem Database

VES

UniProt Database

P0ABD5P63236P0A9Q5C0SP93O34847B1N1A3Q9HZA7P63235P58229Q9FBB7Q9HXZ2

PubMed Citation Links

12210302002444618838771

BRENDA Database

1.4.3.46.1.1.152.3.1.1451.4.3.31.4.3.21

FooDB Database

ACToR Database

Protein Data Bank

NMRShiftDB Database

HMDB Database

Gmelin ID

CompTox Database

SureChEMBL Database

BindingDB Database

Registration numbers

Properties

Related Proteins

Related Proteins

Molecular Spectra

No Data Available

Click here to submit data

Molecule Details

MP Biomedicals

02156469

(Tetrahydropyrrole)
1 ml = approx. 0.86 g

Wikipedia

Pyrrolidine

Sigma Aldrich

W352306

Packaging
1 kg in glass bottle

W352316

Packaging
1 kg in glass bottle
1 sample in glass bottle
8 kg in steel drum

P73803

Packaging
5, 100, 500 mL in glass bottle

394238

Packaging
1 L in Sure/Seal™
100 mL in Sure/Seal™

TRC

P997950

A heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds, namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase N inhibitors (APNIs).

ChEBI

CHEBI:33135

A cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family.

Molecule Details

References

PubChem Literature

From Data Sources

• Gragutan, I. et al.: Beil. J. Org. Chem., 7, 699 (2010)

• Li, X. et al.: Mini-Rev. Med. Chem., 10, 794 (2010)

• A convenient procedure for the conversion of carbonyl compounds to their pyrrolidine enamines involves reaction with pyrrolidine, either neat or in ethereal solution, in the presence of magnesium sulfate: Org. Prep. Proced. Int., 8, 211 (1976).

• Has been widely used in the Leimgruber-Batcho indole synthesis by the reductive cyclization of pyrrolidine ortho-nitro enamines; see N,N-Dimethylformamide dimethyl acetal, A15350.

References

Bioactivity

PubChem BioAssay

Bioactivity

Navigation

General Information

Calculated Properties

• RDKit

• JChem

Data Source

• Commercial Catalog

• Academic Data

Names and Identifiers

• Synonyms

• IUPAC name

• IUPAC Traditional name

Registration numbers

• PubChem CID

• CHEMBL

• Beilstein Number

• MDL Number

• FEMA ID

• CAS Number

• CHEBI ID

• Wikipedia Title

• Chemspider ID

• Unique Ingredient Identifier

• Flavis Number

• EC Number

• Merck Index

• PubChem SID

• Council of Europe Number

• Patent number

• MetaboLights Database

• PDBeChem Database

• UniProt Database

• PubMed Citation Links

• BRENDA Database

• FooDB Database

• ACToR Database

• Protein Data Bank

• NMRShiftDB Database

• HMDB Database

• Gmelin ID

• CompTox Database

• SureChEMBL Database

• BindingDB Database

• PDB Bank

• MP Biomedicals

• Wikipedia

• Sigma Aldrich

• TRC

• ChEBI

Molecule Details

References

• PubChem Literature

• From Data Sources

Bioactivity

• PubChem BioAssay

Synonyms

IUPAC name

pyrrolidine

IUPAC Traditional name

pyrrolidine

MP Biomedicals

02156469

(Tetrahydropyrrole)
1 ml = approx. 0.86 g

Sigma Aldrich

W352306

Packaging
1 kg in glass bottle

W352316

Packaging
1 kg in glass bottle
1 sample in glass bottle
8 kg in steel drum

P73803

Packaging
5, 100, 500 mL in glass bottle

394238

Packaging
1 L in Sure/Seal™
100 mL in Sure/Seal™

TRC

P997950

A heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds, namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase N inhibitors (APNIs).

ChEBI

CHEBI:33135

A cyclic amine whose five-membered ring contains four carbon atoms and one nitrogen atom; the parent compound of the pyrrolidine family.

From Data Sources

• Gragutan, I. et al.: Beil. J. Org. Chem., 7, 699 (2010)

• Li, X. et al.: Mini-Rev. Med. Chem., 10, 794 (2010)

• Has been widely used in the Leimgruber-Batcho indole synthesis by the reductive cyclization of pyrrolidine ortho-nitro enamines; see N,N-Dimethylformamide dimethyl acetal, A15350.

Beilstein Number

MDL Number

Wikipedia Title

Chemspider ID

Unique Ingredient Identifier

LJU5627FYV

Flavis Number

14.064

Council of Europe Number

10491

PDBeChem Database

VES

PubMed Citation Links

12210302002444618838771

FooDB Database

ACToR Database

Protein Data Bank

NMRShiftDB Database

HMDB Database

CompTox Database

SureChEMBL Database

BindingDB Database

Physical Property

Safety Information

Highly Flammable/Corrosive/Harmful/Lachrymatory/Air Sensitive/Store under Argon

Air Sensitive

Download link

Product Information

Pharmacology Properties

no known allergens, no known allergens

Risk Statements

R:11-22-34

R11 20/21/22 35

11-20/22-35

11-20/22-34

RTECS

UX9650000

Safety Statements

S:16-27/28-36/37/39-46-64

S16 26 28 36/37 45

16-26-36/37/39-45

European Hazard Symbols

Flammable (F)

Corrosive (C)

Harmful (X)

NFPA704

Main Hazard

highly flammable, harmful, corrosive, mutagen

GHS Pictograms

Flammable gases, category 1

Flammable aerosols, categories 1,2

Flammable liquids, categories 1,2,3

Self-reactive substances and mixtures, Types B,C,D,E,F

Pyrophoric liquids, category 1

Pyrophoric solids, category 1

Self-heating substances and mixtures

Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3

Organic peroxides, Types B,C,D,E,F

Acute toxicity (oral, dermal, inhalation), category 4

Skin irritation, category 2

Eye irritation, category 2

Skin sensitisation, category 1

Specific Target Organ Toxicity – Single exposure, category 3

Corrosive to metals, category 1

Skin corrosion, categories 1A,1B,1C

Serious eye damage, category 1

Explode Limits

10.6 %

GHS Hazard statements

H225-H302+H332-H314

H225-H314-H318-H302-H332

Packing Group

Hazard Class

UN Number

1922

UN1922

GHS Signal Word

Danger

Personal Protective Equipment

Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

GHS Precautionary statements

P210-P280-P305+P351+P338-P310

P210-P280-P305+P351+P338-P308+P313

RID/ADR

UN 1922 3/PG 2

German water hazard class

TSCA Listed

是

Purity

Empirical Formula (Hill Notation)

C4H9N

Purified By

redistillation

Impurities

≤0.5% water

≤1% water

Cation Traces

Molecule

ID:74386