Molecule

S2573  

Research Area: Cancer
Biological Activity:
Tetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. Tetracaine hydrochloride (Pontocaine) is used to block temporarily the pain "message" that is sent along the nerves that connect the eyes to the brain. Tetracaine hydrochloride (Pontocaine) is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. In addition, tetracaine serves as an allosteric blocker of channel function. At low concentrations, tetracaine gives rise to an initial prevention of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely. [1]References on Tetracaine HCl (Pontocaine)[1] http://en.wikipedia.org/wiki/Tetracaine, ,

02152107 

Hydrochloride
Crystalline

T7508 

Application
眼用局部麻醉药；用于脊髓麻醉
Biochem/physiol Actions
阻断 Ca2+ 从肌浆网的电压敏感性释放。

T7645 

Application
眼用局部麻醉药；用于脊髓麻醉
Biochem/physiol Actions
阻断 Ca2+ 从肌浆网的电压敏感性释放。
包装
Supplied in amber screw-cap vials

T3937 

Application
眼用局部麻醉药；用于脊髓麻醉
Biochem/physiol Actions
阻断 Ca2+ 从肌浆网的电压敏感性释放。

PHR1129 

Application
Topical ophthalmic anesthetic; used for spinal anesthesia
Biochem/physiol Actions
Blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum.
General description
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO Guide 34.
Other Notes
Values of analytes vary lot to lot.

T291335 

A local anesthetic used topically in opthalmology.