Molecule

S2567 

Research Area: Cancer
Biological Activity:
Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist. Medroxyprogesterone acetate is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications. Medroxyprogesterone acetate is a more potent derivative of its parent alcohol medroxyprogesterone. While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate ), what is normally being administered is medroxyprogesterone 17-acetate and not medroxyprogesterone. Medroxyprogesterone acetate has approximately 100 fold higher binding affinity and transactivation potency compared to medroxyprogesterone. [1][2]

M1629 

Biochem/physiol Actions
Medroxyprogesterone 17-acetate (MPA) is a synthetic progestin used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis. It is a more potent progestin that the nonacetylated form.

46412 

Legal Information
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M203560 

Progestogen; an injectable contraceptive.