Research Area: Cancer Biological Activity: Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties. It stimulates the release of norepinephrine in mammals, working as a stimulant. It is produced in nature by several varieties of plants in the family Cactaceae and by some in Acacia. [1]
Biochem/physiol Actions Hordenine is an alkaloid found in plants, e.g. the roots of germinating barley1,2 and marine algae3. It is a metabolite in tyrosine metabolism, biosynthesized from tyramine by two subsequent N-methylations4, it is metabolized by monoamine oxidase5. Hordenine is a sympathomimetic and its pharmacological actions are of interest, as it is occasionally found in post race urine samples6.
A phenethylamine alkaloid with antibacterial and antibiotic properties found mainly in plants from the cactaceae family. It showed effects similar to Cytosine (C998950) and acted as a depressant on the central nervous system (CNS) during animal testing.
Harmful (Xn)