• Reactant for synthesis of fenbufen and ethacrynic acid derivatives1 • Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents2 • Reactant for synthesis of tertiary amides3 • Reactant for preparation of fuconojirimycin derivatives as inhibitors of α-Fucosidases4 • Reactant for total synthesis of oxazinin-3 from 3-indoleglyoxylic acid via an intramolecular addition/cyclization reactions5