CAS 151-06-4|CAS 461-78-9|[2-(4-Chlorophenyl)-1,1-dimethylethyl]amine hydrochloride|chlorphentermine hydrochloride|1-(4-chlorophenyl)-2-methylpropan-2-amine hydrochloride|Clorfentermina Hydrochlorid...

General Information

Structure

Molecular Formula

C₁₀H₁₅Cl₂N

Molecular Mass

220.1388

Exact Mass

219.05815485

Charge

InChI

InChI=1S/C10H14ClN.ClH/c1-10(2,12)7-8-3-5-9(11)6-4-8;/h3-6H,7,12H2,1-2H3;1H

InChIKey

WEJDYJKJPUPMLH-UHFFFAOYSA-N

Canonic Smiles

CC(Cc1ccc(cc1)Cl)(N)C.Cl

Isomeric Smiles

C(Cc1ccc(Cl)cc1)(N)(C)C.Cl

Calculated Properties

JChem

H Acceptors

H Donor

LogD (pH = 5.5)

-0.3357499

LogD (pH = 7.4)

0.06515853

Log P

2.6888719

Molar Refractivity

53.1482

Polarizability

21.005404

Polar Surface Area

26.02

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Academic Data

Commercial Catalog

Data Source

Names and Identifiers

IUPAC name

1-(4-chlorophenyl)-2-methylpropan-2-amine hydrochloride

IUPAC Traditional name

chlorphentermine hydrochloride

Synonyms

[2-(4-Chlorophenyl)-1,1-dimethylethyl]amine hydrochlorideLucofen SA Hydrochloride4-Chloro-α,α-dimethylphenethylamine HydrochlorideClorfentermina HydrochlorideTeramine Hydrochloride(4-Chlorophenyl)-2-methylpropan-2-amine HydrochlorideChlorphentermine Hydrochloride4-Chloro-α,α-dimethyl-1-benzeneethanamine Hydrochloridep-Chloro-α,α-dimethylphenethylamine HydrochlorideDesopimon Hydrochlorideα,α-Dimethyl-4-chlorobenzeneethanamine Hydrochloride1-(p-Chlorophenyl)-2-methyl-2-aminopropane HydrochlorideEffox Hydrochloride

Names and Identifiers

Registration numbers

PubChem SID

CAS Number

PubChem CID

MDL Number

Registration numbers

Properties

Safety Information

TSCA Listed

false

Storage Warning

IRRITANT

MSDS Link

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Product Information

Certificate of Analysis

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Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

TRC

C375080

Chlorphentermine is an anorectic agent. Chlorphentermine is the 4-chloro derivative of the better known appetite suppressant Phentermine (P318830). Chlorphentermine is structurally related to amphetamine but is a relatively weak stimulant with little abus

Molecule Details

References

PubChem Literature

From Data Sources

• Jun, H.W. et al.: Can. J. Pharmac. Sci., 4, 27 (1962)

• Luellmann, H. et al.: J. Pharm. Pharmacol., 25, 239 (1962)

• Gylys, J.A. et al.: J. Pharmacol. Exp. Therap., 137, 365 (1962)

References

Bioactivity

PubChem BioAssay

Bioactivity

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