CAS 5464-78-8|CAS 35386-24-4|1-(2-METHOXYPHENYL) PIPERAZINE|1-(2-methoxyphenyl)piperazine|2-MPP|1-(2-methoxyphenyl)piperazine|D 15157|1-(2-Methoxyphenyl)piperazine|1-(o-Anisyl)piperazine|1-(o-Methox...

General Information

Structure

Molecular Formula

C₁₁H₁₆N₂O

Molecular Mass

192.25754

Exact Mass

192.12626314

Charge

InChI

InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3

InChIKey

VNZLQLYBRIOLFZ-UHFFFAOYSA-N

Canonic Smiles

COc1ccccc1N1CCNCC1

Isomeric Smiles

N1(CCNCC1)c1c(cccc1)OC

Calculated Properties

JChem

H Acceptors

H Donor

LogD (pH = 5.5)

-1.6008211

LogD (pH = 7.4)

-0.06333706

Log P

1.3876901

Molar Refractivity

57.7052

Polarizability

22.153334

Polar Surface Area

24.5

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Names and Identifiers

IUPAC Traditional name

1-(2-methoxyphenyl)piperazine

Synonyms

1-(2-METHOXYPHENYL) PIPERAZINE2-MPP1-(2-Methoxyphenyl)piperazineN-(2-Methoxyphenyl)piperazine1-(o-Anisyl)piperazine1-(o-Methoxyphenyl)piperazine1-(2-Methoxyphenyl)piperazine1-(o-Methoxyphenyl)-piperazine1-(2-Methoxyphenyl)piperazine1-(2-甲氧苯基)哌嗪N-(o-Methoxyphenyl)piperazineo-Methoxyphenylpiperazine1-[2-(Methyloxy)phenyl]piperazineD 151571-(2-Methoxyphenyl)-piperazine1-(o-METHOXYPHENYL)PIPERAZINE

IUPAC name

1-(2-methoxyphenyl)piperazine

Names and Identifiers

Registration numbers

CAS Number

EC Number

MDL Number

Beilstein Number

PubChem SID

2488387224896714160995458

PubChem CID

1346

Registration numbers

Properties

Pharmacology Properties

Gene Information

mouse ... Htr3a(15561)rat ... Adra1a(29412), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr7(65032)

Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

MP Biomedicals

02151629

Hydrochloride
Selective 5-HT1 receptor agonist
Crystalline
Purity: 98-99%

05212491

MP Biomedicals Rare Chemical collection

Sigma Aldrich

M22601

Packaging
5, 25 g in glass bottle

65225

Caution
may solidify at room temperature

TRC

M266220

A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).

Molecule Details

References

PubChem Literature

From Data Sources

• Byrska, B. et al.: Zagadnien Nauk Sadowych 81, 101 (2010)

• Cervo, L. et al.: Pharmacol Biochem Be 82, 727 (2005)

References

Bioactivity

PubChem BioAssay

Bioactivity

Names and Identifiers

IUPAC Traditional name

1-(2-methoxyphenyl)piperazine

Synonyms

IUPAC name

1-(2-methoxyphenyl)piperazine

Registration numbers

CAS Number

EC Number

MDL Number

Beilstein Number

PubChem SID

2488387224896714160995458

PubChem CID

1346

Molecule Details

MP Biomedicals

02151629

Hydrochloride
Selective 5-HT1 receptor agonist
Crystalline
Purity: 98-99%

05212491

MP Biomedicals Rare Chemical collection

Sigma Aldrich

M22601

Packaging
5, 25 g in glass bottle

65225

Caution
may solidify at room temperature

TRC

M266220

A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).

References

PubChem Literature

From Data Sources

• Byrska, B. et al.: Zagadnien Nauk Sadowych 81, 101 (2010)

• Cervo, L. et al.: Pharmacol Biochem Be 82, 727 (2005)

Bioactivity

PubChem BioAssay

Properties

Pharmacology Properties

Gene Information

mouse ... Htr3a(15561)rat ... Adra1a(29412), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr7(65032)

Molecule

ID:32151