Biochem/physiol Actions Inhibitor of calmodulin-regulated enzymes. It is also believed to directly block calcium channels in smooth muscle cells.1 Other Notes Strong inhibitor of brain Ca2+ calmodulin- dependent phosphodiesterase and of CDR-dependent Ca2+ ATPase2,3
Biochem/physiol Actions Inhibitor of calmodulin-regulated enzymes. It is also believed to directly block calcium channels in smooth muscle cells.1 Caution Binds to glass surfaces in aqueous solutions. Reconstitution Stock solutions may be prepared in DMSO at 5 mM then diluted to 0.01 mM with buffer. DMSO solutions may be stored for several weeks.