CAS 57-85-2|丙酸睾酮|androgen|(1S,2R,10R,11S,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadec-6-en-14-yl propanoate...

General Information

Structure

Molecular Formula

C₂₂H₃₂O₃

Molecular Mass

344.48768

Exact Mass

344.23514488

Charge

InChI

InChI=1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1

InChIKey

PDMMFKSKQVNJMI-BLQWBTBKSA-N

Canonic Smiles

CCC(=O)O[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C

Isomeric Smiles

O([C@@H]1[C@@]2([C@H]([C@H]3[C@@H]([C@@]4(C(=CC(=O)CC4)CC3)C)CC2)CC1)C)C(=O)CC

Calculated Properties

JChem

Acid pKa

19.086855

H Acceptors

H Donor

LogD (pH = 5.5)

4.5070844

LogD (pH = 7.4)

4.5070844

Log P

4.5070844

Molar Refractivity

98.2082

Polarizability

38.92798

Polar Surface Area

43.37

Rotatable Bonds

Lipinski's Rule of Five

true

ALOGPS 2.1

Log P

3.65

LOG S

-4.84

Solubility (Water)

5.02e-03 g/l

Data Source

Academic Data

Commercial Catalog

Data Source

Names and Identifiers

Synonyms

丙酸睾酮4-Androsten-17β-ol-3-one 17-propionate17β-Hydroxy-4-androsten-3-one 17-propionate17β-Propionyloxy-4-androsten-3-oneTestosterone propionateTestosterone PropionateEnarmonAquavironAndrotest PNSCAndrotestonHormotestonNRB 03689AndrolonBio-testiculina(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate丙酸睾丸素Testosteroni propionas(17β)-17-(1-Oxopropoxy)androst-4-en-3-oneTestodrinTestosterone-17-propionateVirormoneTestoviron17β-(Propionyloxy)androst-4-en-3-oneTestrexAgovirin

IUPAC Traditional name

androgen testosterone propionate

IUPAC name

(1S,2R,10R,11S,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-yl propanoate (1S,2R,10R,11S,14S,15S)-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl propanoate

Brand Name

TestexAgovirin

Names and Identifiers

Registration numbers

EC Number

CAS Number

Beilstein Number

MDL Number

PubChem SID

248999942488869216096468846508693

PubChem CID

5995

Registration numbers

Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

Selleck Chemicals

S2558

Biological Activity:
Testosterone propionate (Agovirin) is a direct androgen receptor activator and an indirect certain estrogen receptors activator. Testosterone propionate (Agovirin) increases the level of the IGF-1 hormone which leads to muscle growth. Testosterone propionate (Agovirin) has been used for the increase of the nitrogen in the muscles and this leads to the increase of the proteins in the muscles as well. When the muscle fibers have a lot of proteins, they increase in size and quality. As with other testosterones, testosterone propionate (Agovirin) leads to the increase in the activity of the satellite cells which leads to faster recovery after exercising among others. Testosterone propionate (Agovirin) also prevents muscles from wasting and maintains the quality of the muscles you have gained for some time. When testosterone propionate (Agovirin) comes to fat loss, testosterone propionate (Agovirin) is a leader as testosterone propionate (Agovirin) promotes muscle gain and fat loss. [1][2][3]References on Testosterone propionate (Agovirin)[] TEM, 1998, 9:317-324

DrugBank

DB01420

Drug Groups

approved

Description

An ester of testosterone with a propionate substitution at the 17-beta position. [PubChem]

Indication

Testosterone propionate is an anabolic steroid and a short ester form of testosterone that becomes active in the body. It is often used for muscle mass building.

Pharmacology

Testosterone is a steroid hormone from the androgen group. Testosterone is primarily secreted from the testes of males. In females, it is produced in the ovaries, adrenal glands and by conversion of adrostenedione in the periphery. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. Examples include enhanced libido, energy, immune function, and protection against osteoporosis. On average, the adult male body produces about twenty times the amount of testosterone than an adult female's body does. In the body, this ester form of testosterone is hydrolyzed rapidly and become actively available as testosterone.

Toxicity

Side effects include amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism, hostility, impaired urination, paresthesia, penis disorder, peripheral edema, sweating, and vasodilation.

Affected Organisms

Humans and other mammals

Biotransformation

Testosterone propionate is rapidly hydrolysed into testosterone. Testosterone is metabolized to 17-keto steroids through two different pathways. The major active metabolites are estradiol and dihydrotestosterone (DHT).

Protein Binding

40% of testosterone in plasma is bound to sex hormone-binding globulin and 2% remains unbound and the rest is bound to albumin and other proteins.

Elimination

About 90% of a dose of testosterone given intramuscularly is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6% of a dose is excreted in the feces, mostly in the unconjugated form.

External Links

• [Drugs.com]

MP Biomedicals

05218655

MP Biomedicals Rare Chemical collection

Sigma Aldrich

T1875

Biochem/physiol Actions
Androgen.
Physical form
Photosensitive solid

86540

Other Notes
Sales restrictions may apply

86541

Other Notes
Sales restrictions may apply

46925

Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC

TRC

T155045

Anabolic steroid. Androgen.Controlled substance.

Molecule Details

References

PubChem Literature

From Data Sources

• http://en.wikipedia.org/wiki/Testosterone

• Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1977)

• Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977)

• Nieschlag, E., et al.: Steroids, 68, 965 (1977)

• Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (1977)

References

Bioactivity

PubChem BioAssay

Bioactivity

Navigation

General Information

Calculated Properties

• RDKit

• JChem

• ALOGPS 2.1

Data Source

• Academic Data

• Commercial Catalog

Names and Identifiers

• Synonyms

• IUPAC Traditional name

• IUPAC name

• Brand Name

Registration numbers

• EC Number

• CAS Number

• Beilstein Number

• MDL Number

• PubChem SID

• PubChem CID

Registration numbers

Properties

• Product Information

• Pharmacology Properties

• Safety Information

• Physical Property

Related Proteins

Molecular Spectra

Molecule Details

• Selleck Chemicals

• DrugBank

• MP Biomedicals

• Sigma Aldrich

• TRC

Molecule Details

References

• PubChem Literature

• From Data Sources

Bioactivity

• PubChem BioAssay

Synonyms

IUPAC Traditional name

androgen testosterone propionate

IUPAC name

Brand Name

TestexAgovirin

Beilstein Number

MDL Number

S2558

DB01420

Drug Groups

approved

Description

An ester of testosterone with a propionate substitution at the 17-beta position. [PubChem]

Indication

Testosterone propionate is an anabolic steroid and a short ester form of testosterone that becomes active in the body. It is often used for muscle mass building.

Pharmacology

Toxicity

Side effects include amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism, hostility, impaired urination, paresthesia, penis disorder, peripheral edema, sweating, and vasodilation.

Affected Organisms

Humans and other mammals

Biotransformation

Protein Binding

40% of testosterone in plasma is bound to sex hormone-binding globulin and 2% remains unbound and the rest is bound to albumin and other proteins.

Elimination

External Links

• [Drugs.com]

MP Biomedicals

05218655

MP Biomedicals Rare Chemical collection

Sigma Aldrich