CAS 51-80-9|[(dimethylamino)methyl]dimethylamine|bis(DIMETHYLAMINO METHANE)|[(dimethylamino)methyl]dimethylamine|N,N,N',N'-tetramethylmethanediamine|N,N,N′,N′-Tetramethyldiaminomethane|双(二甲氨基)...

InChI=1S/C5H14N2/c1-6(2)5-7(3)4/h5H2,1-4H3

VGIVLIHKENZQHQ-UHFFFAOYSA-N

H Acceptors

H Donor

LogD (pH = 5.5)

-1.8240026

LogD (pH = 7.4)

-0.10955587

Log P

0.31891492

Molar Refractivity

32.8167

Polarizability

13.012255

Polar Surface Area

6.48

Rotatable Bonds

Lipinski's Rule of Five

true

[(dimethylamino)methyl]dimethylamine

bis(DIMETHYLAMINO METHANE)N,N,N',N'-tetramethylmethanediamineN,N,N′,N′-TetramethyldiaminomethaneBis(dimethylamino)methane双(二甲氨基)甲烷N,N,N′,N′-四甲基甲二胺N,N,N′,N′-Tetramethylmethanediamine四甲基甲烷二胺N,N,N',N'-TetramethylmethylenediamineN,N,N',N'-四甲基亚甲二胺N,N,N'N'-Tetramethyldiaminomethane

IUPAC Traditional name

[(dimethylamino)methyl]dimethylamine

Click here to submit data

05219187

MP Biomedicals Rare Chemical collection

T21407

Packaging
25, 100 g in glass bottle

14790

Other Notes
Reagent used in Mannich reactions1,2,3

• Caution! Theproduct of double lithiation has been reported to explode on drying: Org. Process Res. Dev., 7, 1029 (2003).

• Has been used as a convenient source of the Mannich intermediate: J. Org. Chem., 33, 1719 (1968). For an example (dimethylaminomethyleneation of ferrocene), see: Org. Synth. Coll., 5, 434 (1973). Reaction with o-hydroxy ɑ-aryl acetophenones leads directly to isoflavanones: Synth. Commun., 29, 3895 (1999):