CAS 868-63-3|N,N'-(1,2-DIHYDROXYETHYLENE)-bis-ACRYLAMIDE|N-[1,2-dihydroxy-2-(prop-2-enamido)ethyl]prop-2-enamide|N-[1,2-dihydroxy-2-(prop-2-enamido)ethyl]prop-2-enamide|DHEBA|N,N′-(1,2-Dihydroxyeth...

General Information

Structure

Molecular Formula

C₈H₁₂N₂O₄

Molecular Mass

200.19188

Exact Mass

200.07970687

Charge

InChI

InChI=1S/C8H12N2O4/c1-3-5(11)9-7(13)8(14)10-6(12)4-2/h3-4,7-8,13-14H,1-2H2,(H,9,11)(H,10,12)

InChIKey

ZMLXKXHICXTSDM-UHFFFAOYSA-N

Canonic Smiles

C=CC(=O)NC(C(NC(=O)C=C)O)O

Isomeric Smiles

OC(NC(=O)C=C)C(O)NC(=O)C=C

Calculated Properties

JChem

Acid pKa

11.464695

H Acceptors

H Donor

LogD (pH = 5.5)

-1.000612

LogD (pH = 7.4)

-1.0006455

Log P

-1.0006113

Molar Refractivity

48.1114

Polarizability

18.758928

Polar Surface Area

98.66

Rotatable Bonds

Lipinski's Rule of Five

true

Data Source

Commercial Catalog

Academic Data

Data Source

Names and Identifiers

Synonyms

N,N'-(1,2-DIHYDROXYETHYLENE)-bis-ACRYLAMIDEDHEBAN,N′-(1,2-Dihydroxyethylene)bis-acrylamideN,N′-Bisacryloyl-1,2-dihydroxy-1,2-ethylenediamineN,N′-(1,2-Dihydroxyethylene)bisacrylamideN,N′-(1,2-二羟乙烯)二丙烯酰胺N,N′-二羟乙基双丙烯酰胺N,N'-(1,2-Dihydroxyethylene)bisacrylamide1,2-Bis(acrylamido)ethylene glycolN,N'-(1,2-二羟乙烯)二丙烯酰胺

IUPAC Traditional name

N-[1,2-dihydroxy-2-(prop-2-enamido)ethyl]prop-2-enamide

IUPAC name

N-[1,2-dihydroxy-2-(prop-2-enamido)ethyl]prop-2-enamide

Names and Identifiers

Registration numbers

Beilstein Number

CAS Number

EC Number

MDL Number

PubChem SID

PubChem CID

Registration numbers

Properties

Physical Property

<60 μmho (2% solution)

156 °C (dec.)(lit.)

141-143°C

Properties

Related Proteins

No Data Available

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Molecular Spectra

No Data Available

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Molecule Details

Sigma Aldrich

D9538

Analysis Note
经过测试可用作交联剂，用于回收分离的生物分子。
Application
作为聚丙烯酰胺凝胶的可逆交联剂，能够生成凝胶，该凝胶于室温下在高碘酸稀释溶液 (2%) 中 1-2 小时可溶解。凝胶增溶对于从聚丙烯酰胺凝胶中回收蛋白质非常有用。

294381

Packaging
5, 25 g in glass bottle

37475

Other Notes
Cross-linking agent for polyacrylamide gel electrophoresis that produces a gel which is soluble in dilute periodic acid or dilute aqueous solutions of bases1.

MP Biomedicals

04808331

Purity: 98%
Reversible cross-linker which contains a 1,2-diol structure (periodate sensitive) and two amidomethylol bonds (base cleavable). Useful in forming gradient gels where sample recovery is desired. Gels with DHEBA can be dissolved by incubation in periodic acid or sodium periodate.

Molecule Details

References

PubChem Literature

From Data Sources

• Highlink is a registered trademark of Clariant Group.

References

Bioactivity

PubChem BioAssay

Bioactivity

Data Source

Commercial Catalog

Academic Data

Names and Identifiers

Synonyms

IUPAC Traditional name

N-[1,2-dihydroxy-2-(prop-2-enamido)ethyl]prop-2-enamide

IUPAC name

N-[1,2-dihydroxy-2-(prop-2-enamido)ethyl]prop-2-enamide

Registration numbers

Beilstein Number

CAS Number

EC Number

MDL Number

PubChem SID

PubChem CID

Molecule Details

D9538

294381

Packaging
5, 25 g in glass bottle

37475

Other Notes
Cross-linking agent for polyacrylamide gel electrophoresis that produces a gel which is soluble in dilute periodic acid or dilute aqueous solutions of bases1.

MP Biomedicals

04808331

References

PubChem Literature

From Data Sources

• Highlink is a registered trademark of Clariant Group.

Bioactivity

PubChem BioAssay

Properties

Physical Property

<60 μmho (2% solution)

156 °C (dec.)(lit.)

141-143°C

Molecule

ID:106687