CAS 107-46-0|CAS 3469-26-9|trimethyl[(trimethylsilyl)oxy]silane|2,7-DIMETHOXYNAPHTHALENE|hexamethyldisiloxane|HEXAMETHLDISILOXANE|HEXAMETHYLDISILOXANE|Oxybis(trimethylsilane)|Bis(trimethylsilyl) eth...

InChI=1S/C6H18OSi2/c1-8(2,3)7-9(4,5)6/h1-6H3

UQEAIHBTYFGYIE-UHFFFAOYSA-N

C[Si](O[Si](C)(C)C)(C)C

C[Si](C)(C)O[Si](C)(C)C

H Acceptors

H Donor

LogD (pH = 5.5)

3.0278

LogD (pH = 7.4)

3.0278

Log P

3.0278

Molar Refractivity

36.0308

Polarizability

18.337494

Polar Surface Area

9.23

Rotatable Bonds

Lipinski's Rule of Five

true

trimethyl[(trimethylsilyl)oxy]silane

2,7-DIMETHOXYNAPHTHALENEHEXAMETHLDISILOXANEHEXAMETHYLDISILOXANEOxybis(trimethylsilane)Bis(trimethylsilyl) etherBis(trimethylsilyl) oxideHMDSOHexamethyldisiloxane六甲基二硅氧烷Poly(dimethylsiloxane)六甲基二硅氧烷Hexamethyldisiloxane聚二甲基硅氧烷六甲基二硅氧烷溶液Hexamethyldisiloxane solutionNSC 43346SH 200-0.65cStHX 18LS 7130Volasil DM 0.65Volasil DM 0.65SPEthoxytrimethylsilane-hexamethyldisiloxane CopolymerSWS-F 221六甲基二硅氧烷, NMR gradeDow Corning 200/0.65Dow Corning OS 10KF 96L0.65Hexamethyldisiloxane, NMR gradeSH 200-0.65CSOS 101,1,1,3,3,3-HexamethyldisiloxaneHMDSGlipoxanBelsil DM 0.65PSF-0.65cStDC 0.65cs200SF 0.65

IUPAC Traditional name

hexamethyldisiloxane

Unique Ingredient Identifier

R:10

R11

11-51/53

45-46-11-36/38-48/23/24/25-51/53-65

Click here to submit data

02151249

Used for synthesis of benzoyl chlorides.
1 ml = approx. 0.76 g

05207554

MP Biomedicals Rare Chemical collection

205389

Packaging
5, 100, 500 mL in glass bottle

469300

Packaging
50, 250 mL in poly bottle

326739

Packaging
100 g in glass bottle

611921

Features and Benefits
29Si sensitivity

52630

Other Notes
For a facile silylation of carboxylic acids1,2; As chloride anion acceptor in the synthesis of sulphinic esters3

H294215

A silicon based compound that can be used to create potentially biocompatible materials. Used as a monomer in the synthesis of long chain polysiloxane structures. Used in the methylation of mercury(II) salts.

• Watanabe, N. et al.: Ecotoxic. Env. Safety, 11, 174 (2009)

• Radeva, E. et al.: J. Optoelec. Adv. Mat., 11, 1432 (2009)

• Gandhiraman, R.P. et al.: Plama Proc. Polym., 11, 1432 (2009)

• Silylates primary and sec-alcohols and phenols, in the presence of p-TsOH as catalyst. If the substrate contains acid-sensitive groups, PPTS can be used: Tetrahedron Lett., 4261 (1978). See Appendix 4.

• In the presence of FeCl₃, reacts with benzotrichlorides to give substituted benzoyl chlorides in good yields: J. Chem. Soc., Chem. Commun., 808 (1977).

• Reacts with P₂O₅ to give trimethylsilyl polyphosphate ('PPSE'), a milder and more convenient dehydrating agent then polyphosphoric acid. For examples, and related reagents, see Phosphorus(V) oxide, A13348.

Names and Identifiers

IUPAC name

trimethyl[(trimethylsilyl)oxy]silane

Synonyms

IUPAC Traditional name

hexamethyldisiloxane

Registration numbers

EC Number

CAS Number

PubChem CID

Wikipedia Title

Beilstein Number

Chemspider ID

MeSH Name

Unique Ingredient Identifier

D7M4659BPU

PubChem SID

16209132224852329248596172488208024870583

MDL Number

MFCD00008265

Molecule Details

MP Biomedicals

02151249

Used for synthesis of benzoyl chlorides.
1 ml = approx. 0.76 g

05207554

MP Biomedicals Rare Chemical collection

Wikipedia

Hexamethyldisiloxane

Sigma Aldrich

205389

Packaging
5, 100, 500 mL in glass bottle

469300

Packaging
50, 250 mL in poly bottle

326739

Packaging
100 g in glass bottle

611921

Features and Benefits
29Si sensitivity

52630

Other Notes
For a facile silylation of carboxylic acids1,2; As chloride anion acceptor in the synthesis of sulphinic esters3

TRC

H294215

References

PubChem Literature

From Data Sources

• Watanabe, N. et al.: Ecotoxic. Env. Safety, 11, 174 (2009)

• Radeva, E. et al.: J. Optoelec. Adv. Mat., 11, 1432 (2009)

• Gandhiraman, R.P. et al.: Plama Proc. Polym., 11, 1432 (2009)

• In the presence of FeCl₃, reacts with benzotrichlorides to give substituted benzoyl chlorides in good yields: J. Chem. Soc., Chem. Commun., 808 (1977).

Bioactivity

PubChem BioAssay

Grade

NMR grade

for NMR spectroscopy

NMR reference standard

puriss.

Concentration

25% in benzene-d6 (99.6 atom % D)

NMR tube O.D. × L

5 mm × 8 in.

UN Number

1993

1114

UN1993

EU Hazard Identification Number

RTECS

JM9237000

Australian Hazchem

3YE

Packing Group

EU Classification

European Hazard Symbols

Flammable (F)

Nature polluting (N)

Toxic (T)

Emergency Response Guidebook(ERG) Number

128

Storage Condition

Room Temperature (15-30°C)

Hazard Class

Main Hazard

Highly flammable liquid and vapour
Causes serious eye irritation

NFPA704

GHS Pictograms

Flammable gases, category 1

Flammable aerosols, categories 1,2

Flammable liquids, categories 1,2,3

Self-reactive substances and mixtures, Types B,C,D,E,F

Pyrophoric liquids, category 1

Pyrophoric solids, category 1

Self-heating substances and mixtures

Substances and mixtures, which in contact with water, emit flammable gases, categories 1,2,3

Organic peroxides, Types B,C,D,E,F

Hazardous to the aquatic environment

Acute hazard, category1

Chronic hazard, categories 1,2

Acute toxicity (oral, dermal, inhalation), category 4

Skin irritation, category 2

Eye irritation, category 2

Skin sensitisation, category 1

Specific Target Organ Toxicity – Single exposure, category 3

Respiratory sensitization, category 1

Germ cell mutagenicity, categories 1A,1B,2

Carcinogenicity, categories 1A,1B,2

Reproductive toxicity, categories 1A,1B,2

Specific Target Organ Toxicity – Single exposure, categories 1,2

Specific Target Organ Toxicity – Repeated exposure, categories 1,2

Aspiration Hazard, category 1

GHS Signal Word

Danger

GHS Precautionary statements

P210-P273

P201-P210-P273-P301+P310-P305+P351+P338-P308+P313

P210-P273-P403

Personal Protective Equipment

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RID/ADR

UN 1993 3/PG 2

UN 1114 3/PG 2

GHS Hazard statements

H225-H411

H225-H304-H315-H319-H340-H350-H372-H411

H225-H400-H410

German water hazard class

TSCA Listed

是

Certificate of Analysis

Molecule

ID:103302