Biochem/physiol Actions Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs) which inhibits peptidoglycan chain cross-lining. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases. Application Penicillin G is a narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G potassium salt is used to study murosomes of staphylococci1 and the penicillin-induced lysis of Streptococcus mutans2. Protocols & Applications Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Application Recommended for use in cell culture applications at 100,000 units/L. Solutions should be filter sterilized and stored at 2-8 °C for up to 1 week, -20 °C for extended periods. Solutions are stable at 37 °C for 3 days. Biochem/physiol Actions Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria Mode of Action: Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. Antimicrobial spectrum: Gram-positive bacteria Protocols & Applications Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information
Application Use in cell culture in combination with streptomcyin and other antibiotics. Biochem/physiol Actions Inhibits the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. Antimicrobial spectrum: Gram-positive bacteria Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria Reconstitution 溶液应过滤杀菌,在 2-8°C 下最长可储存一周,在 -20°C 下可长期储存。溶液在 37°C 下可稳定 3 天。
Biochem/physiol Actions Mode of Action: Inhibits bacterial cell wall synthesis.Antimicrobial spectrum: Gram-positive bacteria Legal Information VETRANAL is a trademark of Sigma-Aldrich Co. LLC