物质信息
ID:449181
名称和标识
IUPAC标准名
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
别名
YewtaxanAnzataxPaclitaxelTaxol A
IUPAC传统名
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
数据登录号
CAS号
化合物性质
产品相关信息
应用领域
Biochemical tool extensively used to study cellular shape and function.
Use limited by low solubility and scarce availability of Taxus brevifolia bark
Antileukaemic and antineoplastic agent, esp. against melanoma and ovarian tumours
Also shown to be active against oomycete fungi
生物来源
Isol. from the stem bark of Taxus brevifolia and Taxus cuspidata (Taxaceae)
药理学性质
生物活性机理
Binds to the beta subunit of tubulin
Interferes with the normal function of microtubule growth by hyper-stabilisation of their structure
描述信息
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分子图谱
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参考文献
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