物质信息

ID:394449

名称和标识
别名
PaclitaxelGenetaxylOncoGelTaxolYewtaxanNSC 125973GenaxolPacliexAbraxane(-)-PaclitaxelOnxal
IUPAC传统名
taxol
IUPAC标准名
(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl benzoate
数据登录号
化合物性质
安全信息
保存条件
-20°C Freezer
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产品相关信息
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理化性质
外观
White Solid
熔点
214-216°C
溶解度
Methanol
描述信息
An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic i
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参考文献
• Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1984)
• Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (1984)
• Letourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984)
• Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984)
• Stone, G.W., et al.:
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